Immediate Hypersensitivity Reactions after Use of Tuberculin Skin Testing

Tuberculin Skin Testing in Children

In 1996, the American Academy of Pediatrics (AAP) recommended targeted tuberculin skin testing (TST) of children while discouraging routine TST of children without risk factors for tuberculosis (TB). Recent studies have provided evidence in support of the targeted TST and recommendations that favor risk assessment over universal screening with TST. While evidence for targeted TB testing exists ...

Immediate hypersensitivity to tuberculin. In vivo and in vitro studies.

Immediate responses of hypersensitivity to skin testing with purified derivative of tuberculin (PPD) were observed in 2.3 percent of 3,248 patients seen in an allergy clinic, and the relationship to delayed responses was questioned. Immediate cutaneous reactions to testing with PPD appeared in all age groups and occurred in nonatopic patients but were more common in atopic patients (p less than...

Skin Hypersensitivity Reactions to Preservatives

Preservatives are chemicals that are added to products that contain an aqueous phase. These include cosmetics, topical medications, household products, foods, and industrial products such as glues, paints, dyes, metalworking fluids, and spin finishes. They are biocidal or biostatic, inhibiting the overgrowth of micro-organisms and protecting and retarding the chemical degradation of the product...

Serious allergic reactions following tuberculin skin tests.

Penicillin allergy: anti-penicillin IgE antibodies and immediate hypersensitivity skin reactions employing

300 children considered to have had adverse reactions to penicillin were examined. Informed consent was obtained from the parents. Skin tests were conducted by the scratch/prick and intradermal techniques, using benzylpenicilloyl polylysine conjugate and a mixture of minor determinants of penicillin. Specific anti-penicillin IgE antibodies were estimated by the radioallergosorbent test. There w...